Multicenter Validation of Predictive Sputum Biomarkers in CF (Utah Sputum Study)
Purpose A year- long study, found two candidate biomarkers able to predict clinical outcomes in CF, HMGB-1 and free NE activity. Subjects will be enrolled if able to spontaneously produce sputum. The sputum will be collected at baseline, at time of first pulmonary exacerbation, recovery, and 1 year post baseline.
Study status: Enrolling by physician discretion only
Sponsor: Investigator Initiated, University of Utah, Cystic Fibrosis Center, Cystic Fibrosis Foundation.
Principal Investigator: Cori Daines, MD
Osmara Y. Molina de Rodriguez, MS
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